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If a drug company says, "This is the latest, greatest drug. It's safer for you than anything you've ever seen before, and it'll take away your pain," you should likewise be skeptical and not believe that either. In 1991 the drug companies spent a paltry $55 million on advertising drugs directly to consumers. Over the next 11 years, this increased more than 50-fold to over $3 billion in 2003. Ephedra Fact And Fiction by Mike Fillon, page 77 Pharmaceutical companies are in business to make money; with the exception of over-the-counter medications that will be sold in great numbers, the only way a pharmaceutical company can make lots of money is by developing medications that can be patented. At pharmaceutical companies, doctors usually don't make the final decisions—business people make them." No wonder so many patients are not informed either about serious withdrawal syndromes or dependence. They can also move very quickly and deftly to "squash" any negative news about their clients, as well as to promote damaging news about others. These are very expensive ads.D. Glossy ads promote the efficacy or ease of usage of drugs. The requirements brought to a halt the aggressive marketing of notorious drugs like amphetamine antidepressants and barbiturates. Four years later, the pharmaceutical industry got its foot in the door when the FDA agreed to allow "direct-to-consumer" (DTC) advertising.